Proteomics

Dataset Information

0

PAGE4 phosphorylation links MED12 G44D mutation to uterine fibroid progression


ABSTRACT: Uterine leiomyomas (ULs, or fibroids) are the most prevalent clinically significant tumors in reproductive-aged women, frequently causing abnormal uterine bleeding, pelvic pain, and infertility. Although surgical resection is effective for these benign neoplasms, the development of non-invasive, targeted therapies is an urgent clinical need. To bridge the gap between genotype and phenotype in ULs, we employed an integrated multi-omics strategy focused on the recurrent MED12 p.G44D mutation.

INSTRUMENT(S): timsTOF, Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Markku Varjosalo  

PROVIDER: MSV000100276 | MassIVE | Thu Dec 18 08:44:00 GMT 2025

REPOSITORIES: MassIVE

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2025-08-25 | PXD051220 | Pride
2011-05-09 | E-GEOD-23339 | biostudies-arrayexpress
2020-05-01 | GSE138346 | GEO
2020-05-01 | GSE138344 | GEO
2024-08-13 | PXD054389 | Pride
2021-06-15 | GSE165321 | GEO
2011-05-09 | GSE23339 | GEO
2024-08-29 | GSE273927 | GEO
2023-06-12 | GSE224093 | GEO
2021-09-09 | PXD020109 | Pride