Aldehyde dehydrogenases are dual-function enzymes that oxidizes both alcohols and aldehydes

ABSTRACT: This dataset supports a study redefining the functional scope of the Aldehyde Dehydrogenase (ALDH) superfamily as dual-function Alcohol and Aldehyde Dehydrogenases (AALDH). While ALDH2 is classically known for acetaldehyde detoxification, we demonstrate through biochemical and cellular approaches that it possesses robust, intrinsic alcohol dehydrogenase activity.

INSTRUMENT(S): Triple Quad 5500+, AB SCIEX, Triple TOF X500B, AB SCIEX

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Shixian Lin  

PROVIDER: MSV000100430 | MassIVE | Sat Jan 10 04:56:00 GMT 2026

REPOSITORIES: MassIVE