Dataset Information

Blood pseudotargeted metabolome of moyamoya disease

ABSTRACT:

We aimed to identify specific metabolomic changes and biomarkers for the differential clinical diagnosis of different subtypes of moyamoya disease (MMD). We conducted an pseudotargeted metabolomics analysis and pseudotargeted metabolomics analysis revealed decreased LPC expression in patients with MMD. LPC 16:1-2 expression was significantly decreased in patients with ischemic MMD while LPC 22:1 expression was significantly reduced in both ischemic and hemorrhagic MMD.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase, Liquid Chromatography MS - positive - reverse phase

PROVIDER: MTBLS10304 | MetaboLights | 2024-10-31

REPOSITORIES: MetaboLights

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Dataset's files

Source:

			Action	DRS
	SERUM-NEG.wiff	Wiff
	SERUM-NEG.wiff.scan	Wiff
	SERUM-POS.wiff	Wiff
	SERUM-POS.wiff.scan	Wiff
	a_MTBLS10304_LC-MS_negative_reverse-phase_metabolite_profiling.txt	Txt

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Publications

Metabolomic signatures associated with pathological angiogenesis in moyamoya disease.

He Shihao S Wang Yanru Y Liu Ziqi Z Zhang Junze J Hao Xiaokuan X Wang Xilong X Zhou Zhenyu Z Wang Rong R Zhao Yuanli Y

Clinical and translational medicine 20231201 12

PMID: 38037492

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