Dataset Information
Neuropeptide SP protects against colitis and linked anxiety-like behavior via gut microbiota and metabolite inositol: A multi-omics analysis of the gut-brain axis
Ontology highlight
ABSTRACT: The gut-brain axis facilitates two-way communication between gut inflammation and psychiatric comorbidities associated with inflammatory bowel disease (IBD). In this study, we examined the neuroprotective effects of the neuropeptide substance P (SP) on colitis. Taking into account the interactions between the intestinal microbiota and host metabolism, along with the influence of microbiota-derived metabolites on gut-brain signaling, we conducted an untargeted metabolomic analysis.
INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase, Liquid Chromatography MS - positive - reverse phase
PROVIDER: MTBLS11203 | MetaboLights | 2025-11-18
REPOSITORIES: MetaboLights
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| AX112-ZX01-0101-neg-QC-1.raw | Raw | |||
| AX112-ZX01-0101-neg-QC-2.raw | Raw | |||
| AX112-ZX01-0101-neg-QC-3.raw | Raw | |||
| AX112-ZX01-0101-neg-QC-4.raw | Raw | |||
| AX112-ZX01-0101-neg-QC-5.raw | Raw |
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