Metabolomics

Dataset Information

Gut symbiotic bacteria-derived nicotinic acid regulates Bactrocera dorsalis reproduction


ABSTRACT:

Depletion of gut commensal bacteria significantly reduced nicotinic acid (NA) levels in the hemolymph and ovaries of Bactrocera dorsalis, leading to impaired ovarian development. This inhibition was reversed by exogenous NA supplementation. We identified Enterobacter hormaechei as a key NA-producing gut symbiont. Recolonization with E. hormaechei restored NA levels in both the hemolymph and ovaries, thereby rescuing ovarian development in B. dorsalis.

INSTRUMENT(S): Liquid Chromatography MS - positive - reverse phase

PROVIDER: MTBLS12798 | MetaboLights | 2025-07-30

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
NA_NAM20240614.wiff Wiff
NA_NAM20240614.wiff.scan Wiff
NA_NAM20241022.wiff Wiff
NA_NAM20241022.wiff.scan Wiff
NA_NAM20241023_gm.wiff Wiff
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