Metabolomics

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Untargeted LC-MS metabolomics of RANKL-differentiated Bone Marrow–Derived Macrophages ± Bacillus Calmette–Guérin (BCG) exposure


ABSTRACT:

To investigate the metabolites and pathways modulated by BCG in RANKL-differentiated macrophages, thereby elucidating the metabolic mechanisms underlying BCG-induced macrophage activation, BMMs were stimulated with 50 ng/mL RANKL for 5 days to generate osteoclast-like cells. Subsequently, one group of cells was subjected to an additional 4-hour challenge with BCG (MOI = 10).

INSTRUMENT(S): Liquid Chromatography MS - alternating - reverse phase

PROVIDER: MTBLS12992 | MetaboLights | 2026-03-31

REPOSITORIES: MetaboLights

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