Metabolomics

Dataset Information

Metabolic profiling reveals CAD as a central metabolic signaling node


ABSTRACT: LC MS metabolite profiling and carbon tracing were used to show that the pyrimidine synthesis enzyme CAD regulates glycolysis and branching into pentose phosphate and serine synthesis pathways to support cancer cell proliferation.

INSTRUMENT(S): Liquid Chromatography MS positive reverse phase, Liquid Chromatography MS negative reverse phase

PROVIDER: MTBLS13498 | MetaboLights | 2026-02-03

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
13C-glucose-10h-shPHGDH-AAA-1.raw Raw
13C-glucose-10h-shPHGDH-AAA-2.raw Raw
13C-glucose-10h-shPHGDH-AAA-3.raw Raw
13C-glucose-10h-shPHGDH-EED-1.raw Raw
13C-glucose-10h-shPHGDH-EED-2.raw Raw
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