Ontology highlight
ABSTRACT:
INSTRUMENT(S): Liquid Chromatography MS -
SUBMITTER: Johannes Hartl
PROVIDER: MTBLS1402 | MetaboLights | 2020-10-15
REPOSITORIES: MetaboLights
Hartl Johannes J Kiefer Patrick P Kaczmarczyk Andreas A Mittelviefhaus Maximilian M Meyer Fabian F Vonderach Thomas T Hattendorf Bodo B Jenal Urs U Vorholt Julia A JA
Nature metabolism 20200203 2
Cell cycle progression requires the coordination of cell growth, chromosome replication, and division. Consequently, a functional cell cycle must be coupled with metabolism. However, direct measurements of metabolome dynamics remained scarce, in particular in bacteria. Here, we describe an untargeted metabolomics approach with synchronized <i>Caulobacter crescentus</i> cells to monitor the relative abundance changes of ~400 putative metabolites as a function of the cell cycle. While the majority ...[more]