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Bioactivities of Streptomyces spp. Against selected Oral Pathogens and In silico Streptenol B interaction on pgaB of Aggregatibacter actinomycetemcomitans

ABSTRACT: Periodontal disease is an inflammatory condition affecting the tissues supporting the teeth. Biofilm formation by oral pathogens such as Aggregatibacter actinomycetemcomitans (AA) and Pseudomonas aeruginosa (PA) contribute to persistent infections and antibiotic resistance. This study evaluated the antibacterial, antibiofilm, and metabolomic profiles of Streptomyces strains SUKB 28, SUKB 32, and SUK 48 against AA and PA. Besides, this study evaluates in silico optimization of streptenol derivatives of SUKB 28 to virulence receptor of AA, pgaB.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse-phase, Liquid Chromatography MS - positive - reverse-phase

PROVIDER: MTBLS14826 | MetaboLights | 2026-06-23

REPOSITORIES: MetaboLights

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			Action	DRS
	a_MTBLS14826_LC-MS_negative_reverse-phase.txt	Txt
	a_MTBLS14826_LC-MS_positive_reverse-phase.txt	Txt
	i_Investigation.txt	Txt
	m_MTBLS14826_LC-MS_positive_reverse-phase_v2_maf.tsv	Tabular
	s_MTBLS14826.txt	Txt

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