Metabolomic profiling of zebrafish DSS-induced colitis intervened by Akkermansia muciniphila-derived extracellular vesicles (AmEVs)

ABSTRACT: This study performs untargeted metabolomics analysis on intestinal tissues of DSS-induced colitis zebrafish models to uncover the metabolic regulatory mechanisms of AmEVs. We compared intestinal metabolite profiles between two experimental groups: DSS-induced colitis model group and AmEV intervention group. Differential metabolites were screened to explore how AmEVs alleviate DSS-triggered intestinal inflammation and restore damaged intestinal barrier function in zebrafish.

INSTRUMENT(S): Liquid Chromatography MS - alternating - reverse-phase

PROVIDER: MTBLS14855 | MetaboLights | 2026-07-22

REPOSITORIES: MetaboLights