Metabolomics

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Whole genome sequencing and targeted metabolomics of multidrug-resistant Klebsiella pneumoniae KP21-10C


ABSTRACT: This study investigates multidrug-resistant Klebsiella pneumoniae KP21-10C using whole genome sequencing and targeted energy metabolomics. Genomic sequencing data were generated to characterize the bacterial genome, and targeted LC-MS/MS metabolomics was performed to quantify energy metabolism-related metabolites under doxycycline monotherapy and cepharanthine hydrochloride plus doxycycline combination treatment.

INSTRUMENT(S): Liquid Chromatography MS - alternating - hilic, Liquid Chromatography MS - alternating - reverse-phase

PROVIDER: MTBLS14858 | MetaboLights | 2026-06-25

REPOSITORIES: MetaboLights

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