Metabolomics

Dataset Information

Gut Microbiota-Mediated Tryptophan Metabolism Plays Dual Effects in Diffuse Large B-Cell Lymphoma via Regulating 3-IAA/5-HTP Balance and Antitumor Immunity


ABSTRACT: Timing-dependent tryptophan diets differentially modulate DLBCL outcomes via microbiota-derived 3-IAA (pre-inoculation, anti-tumor) versus 5-HTP (post-inoculation, pro-tumor), with pectin restoring microbial balance to enable a timed tryptophan-pectin precision nutrition strategy for enhanced immunotherapy.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse-phase, Liquid Chromatography MS - positive - reverse-phase

PROVIDER: MTBLS15570 | MetaboLights | 2026-09-07

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
NEG_Ha18HN_CC.raw Raw
NEG_Ha18HN_CCY.raw Raw
NEG_Ha18HN_CHC.raw Raw
NEG_Ha18HN_CL.raw Raw
NEG_Ha18HN_CLY_0.raw Raw
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