Ontology highlight
ABSTRACT:
INSTRUMENT(S): Bruker
SUBMITTER: Martina Vermathen
PROVIDER: MTBLS156 | MetaboLights | 2015-01-16
REPOSITORIES: MetaboLights
PloS one 20150529 5
(1)H high resolution magic angle spinning (HR-MAS) NMR spectroscopy was applied in combination with multivariate statistical analyses to study the metabolic response of whole cells to the treatment with a hexacationic ruthenium metallaprism [1](6+) as potential anticancer drug. Human ovarian cancer cells (A2780), the corresponding cisplatin resistant cells (A2780cisR), and human embryonic kidney cells (HEK-293) were each incubated for 24 h and 72 h with [1](6+) and compared to untreated cells. D ...[more]