Untargeted Metabolomics Study of Cur-EGCG Self-Assembled Nanoparticle Systems in Intervening WSSV Infection in Crayfish

ABSTRACT: This study employed Untargeted LC-MS/MS metabolomics to analyze changes in the metabolic profile of crayfish following WSSV infection after intervention with the Cur-EGCG self-assembled nanoscale system (CE SA). The experiment included WSSV and CE SA treatment groups. Through multivariate statistical analysis, screening for differentially expressed metabolites, and metabolic pathway analysis, changes in the metabolic profiles of crayfish under different treatment conditions were compared. The study aims to elucidate the characteristics of host metabolic remodeling following CE SA intervention in WSSV infection and to identify key differentially expressed metabolites and metabolic pathways associated with viral infection and CE SA intervention, thereby providing a metabolomic basis for further research into the anti-WSSV effects of CE SA and its potential biological mechanisms.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse-phase, Liquid Chromatography MS - positive - reverse-phase

PROVIDER: MTBLS15908 | MetaboLights | 2026-10-04

REPOSITORIES: MetaboLights