Ontology highlight
ABSTRACT:
INSTRUMENT(S): Liquid Chromatography MS - negative - hilic
SUBMITTER: Veronika KuchaÅová Pettersen
PROVIDER: MTBLS1679 | MetaboLights | 2022-01-14
REPOSITORIES: MetaboLights
van Tilburg Bernardes Erik E Pettersen Veronika Kuchařová VK Gutierrez Mackenzie W MW Laforest-Lapointe Isabelle I Jendzjowsky Nicholas G NG Cavin Jean-Baptiste JB Vicentini Fernando A FA Keenan Catherine M CM Ramay Hena R HR Samara Jumana J MacNaughton Wallace K WK Wilson Richard J A RJA Kelly Margaret M MM McCoy Kathy D KD Sharkey Keith A KA Arrieta Marie-Claire MC
Nature communications 20200522 1
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fungi, or both to differentiate the causal role of fungi on microbiome assembly, immune development, susceptibility to colitis, and airway inflammation. Fungal colonization promotes major shifts in bacte ...[more]