The protocols and data for human samples are reported in study MTBLS162.
INSTRUMENT(S): Exactive (Thermo Scientific)
SUBMITTER: Jules Griffin
Eiden Michael M Koulman Albert A Hatunic Mensud M West James A JA Murfitt Steven S Osei Michael M Adams Claire C Wang Xinzhu X Chu Yajing Y Marney Luke L Roberts Lee D LD O'Rahilly Stephen S Semple Robert K RK Savage David B DB Griffin Julian L JL
Genome medicine 20150628
<h4>Background</h4>Evidence from several recent metabolomic studies suggests that increased concentrations of triacylglycerols with shorter (14-16 carbon atoms), saturated fatty acids are associated with insulin resistance and the risk of type 2 diabetes. Although causality cannot be inferred from association studies, patients in whom the primary cause of insulin resistance can be genetically defined offer unique opportunities to address this challenge.<h4>Methods</h4>We compared metabolite prof ...[more]