Ontology highlight
ABSTRACT:
INSTRUMENT(S): LCT Premier XE (Waters)
SUBMITTER: Ilka Abreu
PROVIDER: MTBLS450 | MetaboLights | 2018-01-30
REPOSITORIES: MetaboLights
Davoine Celine C Abreu Ilka N IN Khajeh Khalil K Blomberg Jeanette J Kidd Brendan N BN Kazan Kemal K Schenk Peer M PM Gerber Lorenz L Nilsson Ove O Moritz Thomas T Björklund Stefan S
PloS one 20170622 6
Mediator is a multiprotein transcriptional co-regulator complex composed of four modules; Head, Middle, Tail, and Kinase. It conveys signals from promoter-bound transcriptional regulators to RNA polymerase II and thus plays an essential role in eukaryotic gene regulation. We describe subunit localization and activities of Mediator in Arabidopsis through metabolome and transcriptome analyses from a set of Mediator mutants. Functional metabolomic analysis based on the metabolite profiles of Mediat ...[more]