Metabolomics

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Metabolome analysis reveal key regulatory pathways of feed conversion efficiency of oriental river prawn Macrobrachium nipponense


ABSTRACT:

A total of 445 and 247 differently expressed metabolites (DEMs) were identified in the hepatopancreas and muscle. In addition, 11 KEGG pathways, which mainly include lysine biosynthesis, lysine degradation, aminoacyl-tRNA biosynthesis and purine metabolism, were significantly enriched in hepatopancreas. Also, 14 KEGG pathways, which mainly include pyrimidine metabolism, glutathione metabolism, nitrogen metabolism and mTOR signaling pathway, were significantly enriched in muscle. The metabonomic analysis revealed that the feed conversion efficiency of M. nipponense was affected considerably by amino acid, lipid and nucleotide metabolism. Hence, different RFI groups of M. nipponense have various metabolic capability processes. The differences in response to immunity, digestion and absorption of nutrients may be the critical elements related to the variation of RFI.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase, Liquid Chromatography MS - positive - reverse phase

PROVIDER: MTBLS6663 | MetaboLights | 2023-02-28

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
H-He_L-He Differential metabolite.xlsx Xlsx
H-M_L-M Differential metabolite.xlsx Xlsx
N-H-He2-1.raw Raw
N-H-He2-2.raw Raw
N-H-He2-3.raw Raw
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Publications

Combined transcriptome and metabolome analysis reveal key regulatory genes and pathways of feed conversion efficiency of oriental river prawn Macrobrachium nipponense.

Ling Feiyue F   Fan Yaoran Y   Wang Zefei Z   Xie Nan N   Li Jiale J   Wang Guiling G   Feng Jianbin J  

BMC genomics 20230519 1


<h4>Background</h4>Oriental river prawn Macrobrachium nipponense is an economically important aquaculture species in China, Japan, and Vietnam. In commercial prawn farming, feed cost constitutes about 50 to 65% of the actual variable cost. Improving feed conversion efficiency in prawn culture will not only increase economic benefit, but also save food and protect the environment. The common indicators used for feed conversion efficiency include feed conversion ratio (FCR), feed efficiency ratio  ...[more]

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