Ontology highlight
ABSTRACT:
INSTRUMENT(S): Nuclear Magnetic Resonance (NMR)
SUBMITTER: Wolfram Gronwald
PROVIDER: MTBLS798 | MetaboLights | 2019-07-26
REPOSITORIES: MetaboLights
Zacharias Helena U HU Altenbuchinger Michael M Schultheiss Ulla T UT Samol Claudia C Kotsis Fruzsina F Poguntke Inga I Sekula Peggy P Krumsiek Jan J Köttgen Anna A Spang Rainer R Oefner Peter J PJ Gronwald Wolfram W
Journal of proteome research 20190312 4
Identification of chronic kidney disease patients at risk of progressing to end-stage renal disease (ESRD) is essential for treatment decision-making and clinical trial design. Here, we explored whether proton nuclear magnetic resonance (NMR) spectroscopy of blood plasma improves the currently best performing kidney failure risk equation, the so-called Tangri score. Our study cohort comprised 4640 participants from the German Chronic Kidney Disease (GCKD) study, of whom 185 (3.99%) progressed ov ...[more]