Metabolomics

Dataset Information

0

Transcriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Ovarian data)


ABSTRACT:

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selecting four specific time points. We collected samples of ovarian and uterine tissues from five female Jining Gray goats at each time point: after birth (D1), 2-month-old (M2), 4-month-old (M4) and 6-month-old (M6). By combining transcriptomic sequencing of 40 samples (including rRNA-depleted RNA-seq libraries with 3607.8 million reads and miRNA-seq libraries with 444.0 million reads) and metabolomics analysis, we investigated the transcriptomic mechanisms involved in reproductive regulation in the ovary and uterus during sexual maturation, as well as the changes in metabolites and their functional potential. Additionally, we analyzed blood hormone indices and uterine tissue sections to examine temporal changes. These datasets will provide a valuable reference for the reproductive regulation of the ovary and uterus, as well as the regulation of metabolites during sexual maturation in goats.


Ovarian data is reported in the current study MTBLS9794.

Uterine data is reported in MTBLS9795.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase, Liquid Chromatography MS - positive - reverse phase

PROVIDER: MTBLS9794 | MetaboLights | 2024-05-30

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
HFX11_1721113_CN_QC1.raw Raw
HFX11_1721113_CN_QC2.raw Raw
HFX11_1721113_CN_QC3.raw Raw
HFX11_1721113_CN_QC4.raw Raw
HFX11_1721113_CN_QC5.raw Raw
Items per page:
1 - 5 of 104
altmetric image

Publications

Transcriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation.

Wang Yanyan Y   Wang Jianmin J   Li Qing Q   Xuan Rong R   Guo Yanfei Y   He Peipei P   Duan Qingling Q   Du Shanfeng S   Chao Tianle T  

Scientific data 20240713 1


The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selecting four specific time points. We collected samples of ovarian and uterine tissues from five female Jining Gray goats at each time point: after birth (D1), 2-month-old (M2), 4-month-old (M4), and 6-mont  ...[more]

Similar Datasets

2024-05-30 | MTBLS9795 | MetaboLights
2024-03-30 | GSE262297 | GEO
2024-03-30 | GSE262296 | GEO
2021-02-17 | GSE166842 | GEO
2020-08-26 | GSE144368 | GEO
2015-07-19 | GSE49260 | GEO
2021-12-30 | GSE184343 | GEO
2024-03-08 | MSV000094277 | MassIVE
2017-10-30 | GSE87738 | GEO
2020-07-03 | GSE100773 | GEO