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Early in life exposure studies on human and mouse samples

ABSTRACT: Experiment1: 2 day old baby mice were exposed to hyperoxia (75% O2) continuously for 7 days. Control baby mice were housed in room air (normoxia). Plasma and bronchoalveolar lavage fluid (BALF) were harvested after 7 days of exposure (on Day of life 9). Experiment2: 2 day old baby mice were exposed to room air or hyperoxia for 14 days and subsequently treated with RV1 or sham.Plasma was collected 5 days after treatment. Human tracheal aspirates were collected from prematurely born infants undergoing mechanical ventilation for respiratory distress syndrome in the first week of life.Tracheal aspirate supernatants are submitted for the assay. We would like to measure adenosine, AMP, ADP and ATP levels.

ORGANISM(S): Human Homo Sapiens Mouse Mus Musculus;homo Sapiens Mus Musculus

TISSUE(S): Lung

SUBMITTER: Maureen Kachman

PROVIDER: ST000304 | MetabolomicsWorkbench | Thu Mar 26 00:00:00 GMT 2015

REPOSITORIES: MetabolomicsWorkbench

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