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Lipid profiling of caecal samples from GF mice colonized with B. thetaiotaomicron WT or the ΔSPT mutants (part III)

ABSTRACT: To study Bacteroidetes sphingolipids in intestinal health, we colonized germ-free mice with wild type or a sphingolipid-deficient Bacteroides thetaiotaomicron strain. A lack of Bacteroides derived sphingolipids increased intestinal inflammation, dysregulated innate immunity and altered the host ceramide pool.

ORGANISM(S): Mouse Mus Musculus

TISSUE(S): Intestine

DISEASE(S): Irritable Bowel Syndrome

SUBMITTER: Julian Avila-Pacheco

PROVIDER: ST001127 | MetabolomicsWorkbench | Thu Jan 17 00:00:00 GMT 2019

REPOSITORIES: MetabolomicsWorkbench

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