Metabolomics

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Human fecal metabolome profiles under 3 different dietary terms


ABSTRACT: The gut microbiota produce numerous metabolites that affect host physiology, although the effects of the daily diet on human intestinal metabolome profiles and robustness are not well understood. Here we investigated the robustness of the human intestinal environment through gut microbiome and metabolome profiles in response to daily dietary fluctuations. We analyzed 176 fecal samples from 25 healthy Japanese individuals under three dietary conditions, including heterogeneous and homogeneous diets. Human intestinal metabolome and microbiome profiles were unique to each individual and were robust under daily dietary fluctuation in most cases. Our findings provide insight into the use of intestinal environment information for clinical studies.

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Feces

SUBMITTER: Shinji Fukuda  

PROVIDER: ST002212 | MetabolomicsWorkbench | Wed Jun 29 00:00:00 BST 2022

REPOSITORIES: MetabolomicsWorkbench

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