Project description:Microbiological evaluation of piperacillin-tazobactam alone and in combination with amikacin versus meropenem against extended spectrum beta-lactamase-producing and non-producing Escherichia coli and Klebsiella pneumoniae clinical isolates
Project description:The present study examines changes in global gene expression patterns and in virulence factor-associated genes in an extended spectrum beta-lactamase (ESBL)-producing UPEC (ESBL019) during the morphologic transitions induced by an ineffective antibiotic and in the presence of human primary bladder epithelial cells. The morphological shifts induced by ineffective antibiotics are associated with significant transcriptional virulence alterations in ESBL-producing UPEC, which may affect survival and persistence in the urinary tract.
Project description:Risk factors associated with Extended-Spectrum β-Lactamase Producing Enterobacterales Gut Colonization in Healthy Community Dogs in Israel
