Dataset Information


L. paracasei CNCM i-4034

ABSTRACT: Lactobacillus paracasei CNCM i-4034



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Action DRS
ERR977922.fastq.gz Fastqsanger.gz
ERR977923.fastq.gz Fastqsanger.gz
ERR977924.fastq.gz Fastqsanger.gz
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Human intestinal dendritic cells decrease cytokine release against Salmonella infection in the presence of Lactobacillus paracasei upon TLR activation.

Bermudez-Brito Miriam M   Muñoz-Quezada Sergio S   Gomez-Llorente Carolina C   Matencio Esther E   Bernal María J MJ   Romero Fernando F   Gil Angel A  

PloS one 20120814 8

Probiotic bacteria have been shown to modulate immune responses and could have therapeutic effects in allergic and inflammatory disorders. However, little is known about the signalling pathways that are engaged by probiotics. Dendritic cells (DCs) are antigen-presenting cells that are involved in immunity and tolerance. Monocyte-derived dendritic cells (MoDCs) and murine DCs are different from human gut DCs; therefore, in this study, we used human DCs generated from CD34+ progenitor cells (hemat  ...[more]

Publication: 1/7

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