Genomics

Dataset Information

2


ABSTRACT: The Treatment-Naive Microbiome in New-Onset Crohn`s Disease

PROVIDER: PRJEB13680 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
ERR1370260.fastq.gz Fastqsanger.gz
ERR1370270.fastq.gz Fastqsanger.gz
ERR1370280.fastq.gz Fastqsanger.gz
ERR1370290.fastq.gz Fastqsanger.gz
ERR1370300.fastq.gz Fastqsanger.gz
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Publications


Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked to host pathways that implicate an underlying role for aberrant immune responses to intestinal microbiota. However, patterns of gut microbiome dysbiosis in IBD patients are inconsistent among published studies. Using samples from multiple gastrointestinal locations collected prior to treatment in new-onset cases, we studied the microbiome in the largest pediatric CD cohort to date. An axis defined by an in  ...[more]

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