Project description:Domestication of pig results in modifications of many traits, including fatness traits, which are important in pig production since they have effect on meat quality, fattening efficiency, reproduction and immunity.In this study, we investigate 3D genome organization and transcriptomic characterization of adipose tissues (ATs) between wild boars and Bama pig, a typical indigenous domestic pig in China, to uncover molecular mechanisms of fatness-phenotypic shifts.
Project description:The Moutan Cortex Radicis (MCR) has been used as an analgesic, sedative and anti-inflammatory agent. This study investigated the changes in gene expression by MCR treatment when stimulated with lipopolysaccharide (LPS) in cultured human gingival fibroblasts (HGFs) and the gene expression changes by the MCR when challenged with LPS using a microarray chip.
Project description:In Poland, conducted for years porcine breeding works focused on improving meat content in the carcass without undertaken to accomplish the more effectiveness of fattening indicators that impact on feed efficiency. At present, feeding and feed conversion became important factors that are especially evident in the countries where the production of fattening pigs is conducted in large farms. In the present study, was attempted to indicate pituitary candidate genes depending on feed conversion ratio (FCR) in native Polish pig breed, Złotnicka White. The whole pituitary transcriptome was sequenced using next-generation sequencing technology. The obtained results show the differences in gene expression for pathways associated with hormonal regulation and also with Notch and Wnt signaling. Moreover, it was observed that worse FCR in Złotnicka pigs was associated with a higher fat level in a carcass and a significant higher level of prolactin expression in the pituitary.
Project description:Gene expression data of micro RNA of pig, in the first part of this study, they were analysed for correlation of transcripts levels with body weight and meat quality grade traits