ABSTRACT: EMG produced TPA metagenomics assembly of the Durable coexistence of donor and recipient strains after fecal microbiota transplantation (Impact of faecal microbiota transplantation on the intestinal microbiome in metabolic syndrome patients) data set.
EBI metagenomics (http://www.ebi.ac.uk/metagenomics) provides a free to use platform for the analysis and archiving of sequence data derived from the microbial populations found in a particular environment. Over the past two years, EBI metagenomics has increased the number of datasets analysed 10-fold. In addition to increased throughput, the underlying analysis pipeline has been overhauled to include both new or updated tools and reference databases. Of particular note is a new workflow for tax ...[more]
Project description:We compared the microbiota of paired mouse caecal contents and faeces by applying a multi-omic approach, including 16S rDNA sequencing, shotgun metagenomics, and shotgun metaproteomics. The aim of the study was to verify whether faecal samples are a reliable proxy for the mouse colonic luminal microbiota, as well as to identify changes in taxonomy and functional activity between caecal and faecal microbial communities, which have to be carefully considered when using stool as sample for mouse gut microbiota investigations.
2017-03-31 | PXD004911 | Pride
Project description:EMG produced TPA metagenomics assembly of the Compositional_dynamics_of_intestinal_spore_forming_bacteria (Compositional_dynamics_of_intestinal_spore_forming_bacteria) data set.
| PRJEB24528 | ENA
Project description:EMG produced TPA metagenomics assembly of the Human Faecal Samples Raw sequence reads (human gut metagenome) data set.
| PRJEB24778 | ENA
Project description:EMG produced TPA metagenomics assembly of the Hospital Metagenomics (Colonization and Succession of Hospital-Associated Microbiota) data set.
| PRJEB24821 | ENA
Project description:EMG produced TPA metagenomics assembly of the gut microbiota from an obese human (SRP012035) data set.
| PRJEB25192 | ENA
Project description:EMG produced TPA metagenomics assembly of the Dechlorinating community (Dhgm_1) data set.
Project description:Age-dependent changes of the gut-associated microbiome have been linked to increased frailty and systemic inflammation. This study found that age-associated changes of the gut microbiome of BALB/c and C57BL/6 mice could be reverted by co-housing of aged (22 months old) and adult (3 months old) mice for 30-40 days or faecal microbiota transplantation (FMT) from adult into aged mice. This was demonstrated using high-throughput sequencing of the V3-V4 hypervariable region of bacterial 16S rRNA gene isolated from faecal pellets collected from 3-4 months old adult and 22-23 months old aged mice before and after co-housing or FMT.