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The transcriptional regulator TFB-RF1 activates transcription of a putative ABC transporter in Pyrococcus furiosus

ABSTRACT: The transcriptional regulator TFB-RF1 activates transcription of a putative ABC transporter in Pyrococcus furiosus

PROVIDER: PRJEB25704 | ENA |

REPOSITORIES: ENA

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The transcriptional regulator TFB-RF1 activates transcription of a putative ABC transporter in Pyrococcus furiosus

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Heat and Cold Shock Response in Pyrococcus furiosus

Project description:We designed an experimental setup to investigate the transcriptomic and proteomic responses of the hyperthermophilic archaeon Pyrococcus furiosus to heat and cold shock. P. furiosus is a model organism for studying microbial adaptation to extreme environments, including deep-sea hydrothermal vents with temperature gradients ranging from 1°C to 400°C. We aimed to simulate critical conditions where P. furiosus cannot grow and to examine the immediate response to thermal stress as well as the recovery process.

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