Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Draft genome of an XDR-TB isolate from Nepal

ABSTRACT: Draft genome of an isolate of Extensively-Drug Resistant (XDR) Mycobacterium tuberculosis from Eastern Nepal

PROVIDER: PRJEB35218 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Draft genome of an XDR-TB isolate from Nepal

Project description:Draft genome of an isolate of Extensively-Drug Resistant (XDR) Mycobacterium tuberculosis from Eastern Nepal

| PRJEB35230 | ENA

XDR-TB isolates from Eastern Nepal

Project description:Draft genome of an isolate of Extensively-Drug Resistant (XDR) Mycobacterium tuberculosis from Eastern Nepal

| PRJEB35231 | ENA

Sequencing of the first reported XDR TB isolate in Ireland

Project description:Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis isolate from Ireland.

| PRJEB6629 | ENA

THP-1 cells infected with the clinical isolates of extensively drug-resistant and drug sensitive tuberculosis

2009-04-04 | GSE15539 | GEO

XDR-TB in the WC of SA

Project description:Phylo-epidemiology of extensively drug resistant tuberculosis in the Western Cape Province, South Africa

| PRJEB43283 | ENA

Expression profiling of extensively drug-resistant tuberculosis isolates and H37Rv exposed to anti-TB compounds

2014-01-07 | GSE53843 | GEO

Project description:Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis in Zhejiang, China

| PRJNA392962 | ENA

THP-1 cells infected with the clinical isolates of extensively drug-resistant and drug sensitive tuberculosis

Project description:Extensively drug resistant tuberculosis (XDR-TB) showed many different characteristics including the extreme drug resistance versus the drug sensitive clinical isolates (DS-TB), to know better about the reasons we used the tuberculosis host cells named as THP-1 (one kind of the macrophage cells) to be infected by the XDR-TB and DS-TB.DS strain A36 and the XDR strain B42 and was typical and selected by our lab. Then the total RNA of infected or uninfected THP-1 cells was extract and purified for the analysis by the chip (22K Human Genome chip representing the 21522 ORF of human with the oligonucleotide probe of 70 mer from CapitalBio Corp., Beijing, China). The results reflected the different expressed genes involved in apoptosis, secreted cytokines and signal pathway and so on. Those results might indicate the how the XDR-TB cause the pathogenesis. In this study, the well grown THP-1 cells were separated and cultured in three ampoules. Cells in one ampoules were infected with XDR-TB strain of B42. Cells in another ampoules were infected with DS-TB strain of A36, with the cells in the third one were not infected and just treated with PBS as the control. Then the dual channel method was used for detecting the hybridization of B42 vs the control or A36 vs control. This work was repeated for three times.

2010-06-20 | E-GEOD-15539 | biostudies-arrayexpress

Expression profiling of extensively drug-resistant tuberculosis isolates and H37Rv exposed to anti-TB compounds

Project description:To explore the mechanism of drug resistance, most works focused on resistance associated genetic mutations, whereas concerns for resistance related gene expression are relatively low. Here a global expression analysis was performed between a reference strain H37Rv and two clinical extensively drug-resistant (XDR) strains with three anti-TB drug exposures {isoniazid (INH), capreomycin (CAP), rifampicin (RIF)} Strains were grown in Middlebrook 7H9 broth supplemented with ADC, 0.05% Tween 80 and 0.2% glycerol to an OD600 of 0.5-0.6, and then respectively treated with control (water), 10×MIC INH, 1×MIC RIF and CAP for 6hr.

2014-01-07 | E-GEOD-53843 | biostudies-arrayexpress

Comparative genomic analyses of Multi-Drug Resistant Genomic Analyses of Mycobacterium tuberculosis isolates from Nepal and other geographical locationsfromMulti-Drug Resistant Cases of TB in Nepal

Project description:Comparative genomic analyses of Multi-Drug Resistant Genomic Analyses of Mycobacterium tuberculosis isolates from Nepal and other geographical locationsfromMulti-Drug Resistant Cases of TB in Nepal

| PRJEB48270 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data