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Bacteroides ovatus TSDC16.1-1.4

ABSTRACT: Strain Bacteroides ovatus TSDC16.1-1.4 (species Bacteroides ovatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

PROVIDER: PRJEB3628 | ENA |

REPOSITORIES: ENA

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Bacteroides ovatus TSDC16.1-1.6

Project description:Strain Bacteroides ovatus TSDC16.1-1.6 (species Bacteroides ovatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Bacteroides ovatus TSDC16.1-1.1

Project description:Strain Bacteroides ovatus TSDC16.1-1.1 (species Bacteroides ovatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Bacteroides ovatus TSDC16.1-2.1

Project description:Strain Bacteroides ovatus TSDC16.1-2.1 (species Bacteroides ovatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Bacteroides ovatus TSDC16.1-1.3

Project description:Strain Bacteroides ovatus TSDC16.1-1.3 (species Bacteroides ovatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Bacteroides ovatus TSDC16.1-1.2

Project description:Strain Bacteroides ovatus TSDC16.1-1.2 (species Bacteroides ovatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Bacteroides ovatus TSDC16.1-1.5

Project description:Strain Bacteroides ovatus TSDC16.1-1.5 (species Bacteroides ovatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Bacteroides vulgatus TSDC16.1-1.4

Project description:Strain Bacteroides vulgatus TSDC16.1-1.4 (species Bacteroides vulgatus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Streptococcus TSDC16.1-1.4

Project description:Strain Streptococcus TSDC16.1-1.4 (species Streptococcus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Subdoligranulum variabile TSDC16.1-1.4

Project description:Strain Subdoligranulum variabile TSDC16.1-1.4 (species Subdoligranulum variabile) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.

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Depolymerization of plant cell wall glycans by symbiotic human gut bacteria (Bacteroides ovatus)

Project description:Symbiotic bacteria inhabiting the distal human gut have evolved under intense pressure to utilize complex carbohydrates, predominantly plant cell wall glycans abundant in our diets. These substrates are recalcitrant to depolymerization by digestive enzymes encoded in the human genome, but are efficiently targeted by some of the ~103-104 bacterial species that inhabit this niche. These species augment our comparatively narrow carbohydrate digestive capacity by unlocking otherwise unusable sugars and fermenting them into host-absorbable forms, such as short-chain fatty acids. We used phenotype profiling, whole-genome transcriptional analysis and molecular genetic approaches to investigate complex glycan utilization by two fully sequenced and closely related human gut symbionts: Bacteroides thetaiotaomicron and Bacteroides ovatus. Together these species target all of the common glycosidic linkages found in the plant cell wall, as well as host polysaccharides, but each species exhibits a unique ‘glycan niche’: in vitro B. thetaiotaomicron targets plant cell wall pectins in addition to linkages contained in host N- and O-glycans; B. ovatus uniquely targets hemicellulosic polysaccharides along with several pectins, but is deficient in host glycan utilization. Bacteroides ovatus bacteria were grown either in vitro on defined complex glycan sources, or in vivo in the intestinal tract of gnotobiotic mice fed variable diets. Increased in vitro gene expression was used to indicate the genes required for metabolism of complex glycans and compared to in vivo transcriptional activity to determine expression in the mouse gut.

2011-05-01 | E-GEOD-25575 | biostudies-arrayexpress

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