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Identification of MEF2 binding sites in adult mouse ventricular myocytes

ABSTRACT: Identification of MEF2 binding sites in adult mouse ventricular myocytes

PROVIDER: PRJEB38619 | ENA |

REPOSITORIES: ENA

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Identification of MEF2 binding sites in adult mouse ventricular myocytes

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Project description:Title: Regulation of gene expression through mitogen-activated protein kinase cascades in cardiac myocytes. Description: The aim of this study is to identify the changes in gene expression induced in rat neonatal ventricular myocytes, a well-established cell culture model, by endothelin-1, a known hypertrophic agonist, and to determine which of the changes are mediated through the ERK cascade. This continues TKAC^Ys previous study of the effects of oxidative stress, which induces cardiac myocyte apoptosis.

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