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Biosulfidogenesis in acidic mine pit lakes

ABSTRACT: Acidic mine pit lakes as natural bioreactors: in-situ attenuation mediated by biosulfidogenesis

PROVIDER: PRJEB38636 | ENA |

REPOSITORIES: ENA

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Biosulfidogenesis Mediates Natural Attenuation in Acidic Mine Pit Lakes.

Project description: Not available

| S-EPMC7565709 | biostudies-literature

Aquatic Ecosystems of the Anthropocene: Limnology and Microbial Ecology of Mine Pit Lakes.

Project description: Not available

| S-EPMC8228816 | biostudies-literature

Sediment samples from meromictic pit lakes at Cluff Lake, SK, Canada

Project description:Sediment samples from meromictic pit lakes at Cluff Lake, SK, Canada Raw sequence reads

| PRJNA451196 | ENA

Pit-1 overexpression in the human breast adenocarcinoma MCF-7 cell line

Project description:The aim of the study is to evaluate Pit-1-induced genes in the MCF-7 cell line The Pit-1 transcription factor (also known as POU1F1) plays a critical role in cell differentiation during organogenesis of the anterior pituitary in mammals and is a transcriptional activator for pituitary gene transcription. Increased expression of Pit-1 has been reported in human tumorigenic breast cells. Here, we found that Pit-1 overexpression or knockdown in human breast cancer cell lines induced profound phenotypic changes in the expression of proteins involved in cell proliferation, apoptosis, and invasion. In immunodeficient mice, Pit-1 overexpression induced tumoral growth and promoted metastasis in lung. In patients with invasive ductal carcinoma of the breast and node-positive tumors elevated expression of Pit-1 was significantly and independently associated with the occurrence of distant metastasis. These findings suggest that Pit-1 could help to make a more accurate prognosis in patients with node positive breast cancer and may represent a new therapeutic target (Journal of Clinical Investigation 2010, 120:4289-4302)

2014-12-12 | GSE64101 | GEO

Metatranscriptomics of a revegetated acidic mine wasteland

Project description:Three soil samples have been sequenced to determine the metabolic activities of the microbial communities in situ in a revegetated acidic mine wasteland

| PRJEB42658 | ENA

Pit-1 overexpression in the human breast adenocarcinoma MCF-7 cell line

2014-12-12 | E-GEOD-64101 | biostudies-arrayexpress

Time-resolved in situ transcriptomics of mouse gastric pit cells during postnatal development reveals distinct features from those observed of the whole stomach

Project description:Whole-organ transcriptomic analyses have emerged as a common method for characterizing developmental transitions in mammalian organs. However, it is unclear if all cell types in an organ follow the whole-organ defined developmental trajectory. To investigate the developmental process of mouse postnatal gastric pit cells. Here, using laser capture microdissection to obtain in situ transcriptomic data ranging from postnatal week 1 to week 8.

2022-08-01 | GSE210009 | GEO

RNA-Seq on Malus domestica Braeburn x Cameo lines resistant and susceptible to bitter pit disorder

Project description:Bitter pit is the most important physiological disorder affecting apples. In order to ascertain the genetic bases of its incidence in apple fruit, a mapping population of ‘Braeburn’ (susceptible to bitter pit) × ‘Cameo’ (resistant to bitter pit) cultivars was used to map the trait over two growing seasons. RNA-Seq on pools of RNA extracted from fruits of three resistant and three susceptible to bitter pit progenies at post-fertilization and full maturity stages, permitted us to identify a number of candidate genes underlying genetic resistance/susceptibility to bitter pit.

2018-06-12 | E-MTAB-6190 | biostudies-arrayexpress

Pit Mud

Project description:Pit Mud Raw sequence reads

| PRJNA646030 | ENA

Assessing the Potential Ecological Impacts of Perfluorinated Chemicals (PFCs) in the liver and testis of male largemouth bass (Micropterus salmoides) in Minnesota Lakes

Project description:This study used an emerging analytical technology (cDNA microarrays) to assess the potential effects of PFC exposure on largemouth bass in TCMA lakes. Microarrays simultaneously measure the expression of thousands of genes in various tissues from organisms exposed to different environmental conditions. From this large data set, biomarkers (i.e., genes that are expressed in response to an exposure to known stressors) and bioindicators (e.g., suites of genes that correspond to changes in organism health) can be simultaneously measured to clarify the relationship between contaminant exposure and organism health. Based on current scientific literature, we hypothesized that gene expression patterns would be altered in fish exposed to PFCs (as compared with fish from reference lakes), and that the magnitude of these changes would correspond to the concentrations of PFCs present throughout TCMA lakes. Patterns of gene expression in largemouth bass observed across the TCMA lakes corresponded closely with PFC concentration. Concentrations of PFCs in largemouth bass varied significantly across the sampled lakes, where the lowest concentrations were found in Steiger and Upper Prior Lakes and the highest concentrations were found in Calhoun and Twin Lakes. Patterns of gene expression were most different (relative to controls) in fish with the highest PFC tissue concentrations, where fish from Twin and Calhoun Lakes were observed to have between 5437 and 5936 differentially expressed genes in liver and gonad tissues. Although gene expression patterns demonstrated a high degree of correlation with PFC concentrations, microarray data also suggest there are likely additional factors influencing gene expression patterns in largemouth bass in TCMA lakes.

2014-07-31 | GSE57684 | GEO

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