Project description:Regenerating feathers of the Gouldian finches were collected from heads of moulting individuals from an Australian captive population. Affymetrix microarrays were used to examine gene expression differences between black and red morphs.
Project description:The goal of this study is to compare miRNAs expressed by EGF treated SWAN-71 cells to miRNAs expressed in untreated control SWAN-71 cells to identify micro RNAs which play a role during EGF-mediated SWAN-71 cell invasion
Project description:The goal of this study is to compare miRNAs expressed by HGF treated SWAN-71 cells to miRNAs expressed in untreated control SWAN-71 cells to identify micro RNAs which play a role during HGF-mediated SWAN-71 cell invasion
Project description:The goal of this study is to compare miRNAs expressed by IFN-gamma treated SWAN-71 cells to miRNAs expressed in untreated control SWAN-71 cells to identify micro RNAs which play a role during IFN-gamma-mediated SWAN-71 cells invasion
Project description:Chemical hypoxia by CoCl2 treatment and pro-inflammatory cytokines induced distinct changes in the transcriptome of Swan 71 human trophoblasts.
Project description:Chemical hypoxia by CoCl2 treatment and pro-inflammatory cytokines induced distinct changes in the transcriptome of Swan 71 human trophoblasts. Not Paired. Samples were treated with control treatments (PBS) as well as with CoCl2, IL-1β, and TNFα.
Project description:Genome-wide mRNA expression profiles of 70 primary gastric tumors from the Australian patient cohort. Like many cancers, gastric adenocarcinomas (gastric cancers) show considerable heterogeneity between patients. Thus, there is intense interest in using gene expression profiles to discover subtypes of gastric cancers with particular biological properties or therapeutic vulnerabilities. Identification of such subtypes could generate insights into the mechanisms of cancer progression or lay the foundation for personalized treatments. Here we report a robust gene-xpression-based clustering of a large collection of gastric adenocarcinomas from Singaporean patients [GSE34942 and GSE15459]. We developed and validated a classifier for the three subtypes in Australian patient cohort.