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A collection of Candida albicans aneuploid strains

ABSTRACT: A collection of Candida albicans aneuploid strains

PROVIDER: PRJEB41161 | ENA |

REPOSITORIES: ENA

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A collection of Candida albicans aneuploid strains

Project description:We used C. albicans diploid reference strain SC5314 to obtain aneuploid colonies via selection by drugs. We got a collection of aneuploid strains bearing trisomy of each homolog of each chromosome.

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Project description:We obtained ketoconazole tolerant mutants in Candida albicans after exposing the strain SC5314 to inhibitory concentration of ketoconazole. We did RNA-Seq to compare the transcriptomes of the aneuploid strains versus the parent euploid strain.

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CGH analysis of Candida albicans strains

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Project description:Several aneuploid Candida glabrata strains, each bearing a unique karyotype, were spread on YPD plates. They all exhibited colony size vairations. Randmly 10 large colonies from each strain were sequenced.

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CGH of common Candida albicans strains

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