Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of mouse iBAT with local acetate administration

ABSTRACT: RNA-seq of mouse iBAT with local acetate administration

PROVIDER: PRJEB46096 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

RNA-seq of mouse iBAT with local acetate administration

Project description:Acetate, or CFMB (Gpr43 agonist), or saline were administrate to left lobe of interscapular brown adipose tissue (iBAT) by a catheter guided pump. Tissue were harvested after four and seven days of administration.

2021-11-20 | E-MTAB-10680 | biostudies-arrayexpress

Local administration of IFN-α-iPSC-pMCs alters gene expression profiles in tumor microenvironment.

Project description:Local administration of IFN-α-producing proliferating myeloid cells (IFN-α-iPSC-pMCs) inhibited the tumor growth not only at the treatment site (right) but also at the distant site (left). We identified genes with log fold expression change ≥ 1 or ≤ −1 in untreated versus IFN-α-iPSC-pMC-treated tumors and iPSC-pMC-treated versus IFN-α-iPSC-pMC-treated tumors for treatment or distant site, respectively. Of the overlapping genes differentially expressed in IFN-α-iPSC-pMC-treated mice, 301/671 distant site and 460/928 treated site genes were ISGs, of which 95.3% and 94.7%, respectively, were type I IFN-related. By gene ontology, the up-regulated ISG signatures were enriched for “T cell-mediated immune responses”, “cytolysis”, and “migration of immune cells” associated genes. Collectively, Local administration of IFN-α-iPSC-pMCs alters the tumor microenvironment and propagates molecular signature associated with type I IFN.

2019-02-13 | GSE126279 | GEO

Acetate and B cells

Project description:Mouse spleen B cells were activated with sodium acetate (10 mM) for 5 days and the transcriptome change was determined with microarrays. This experiment determines the effect of acetate on gene expression in B cells.

2018-04-30 | GSE80719 | GEO

Transcriptome profiling of mouse CD8+ T cells in the presence or absence of acetate

Project description:To investigate the role of acetate in T cell survival and the underlying mechanism, transcription profiling was performed on mouse CD8+ T cells treated with or without 10mM acetate for 24h. We then performed gene expression profiling analysis using data obtained from RNA-seq of mouse CD8+ T cells.

2023-06-22 | GSE217411 | GEO

Single-nucleus transcriptome analysis of interscapular brown adipose tissue (iBAT) in Wtapflox/flox and BAT-specific Wtap knockout (BKO) mice

Project description:Purpose: Through Single-nucleus transcriptome analysis, we aim to characterize the changes of cell heterogeneity in iBAT obtained from Wtap-BKO mice compared with that in Wtapflox/flox mice. Methods: Nuclei were isolated from iBAT of Wtap flox/flox and Wtap-BKO mice at 8 weeks old. Each sample was pooled from 4 mice for each group. Conclusion: The Single-nucleus transcriptomes of iBAT in Wtapflox/flox and BKO mice were characterized.

2022-10-20 | GSE202630 | GEO

scRNA-seq of mouse colon after THC administration

Project description:scRNA-seq of mouse colon after THC administration

| PRJNA655180 | ENA

Transcriptome profiling of mouse CD4+ T cells in the presence or absence of acetate

Project description:Transcription profiling was performed on mouse CD4+ T cells treated with or without 10 mM acetate for 24 h. We then performed gene expression profiling analysis using data obtained from RNA-seq of mouse CD4+ T cells.

2023-06-22 | GSE226252 | GEO

Rice acetate treatment

Project description:Rice acetate treatment

| PRJNA476147 | ENA

Analysis of aortic gene expression in ovariectomized ApoE-deficient mice substituted with medroxyprogesterone acetate, norethisterone acetate or placebo

Project description:Agilent 4x44k Whole Mouse Genome v1 Microarrays were used to analyze aortic transcriptome of mice substituted with medroxyprogesterone acetate, norethisterone acetate or placebo after having been ovariectomized. The aim of this experiment was to detect genes regulated in the gestagen-treated groups as compared to placebo that might be involved in thrombotic events

2014-06-30 | GSE57972 | GEO

Local administration of IFN-α-iPSC-pMCs alters gene expression profiles in tumor microenvironment.

Project description:Local administration of IFN-α-iPSC-pMCs alters gene expression profiles in tumor microenvironment.

| PRJNA521845 | ENA