Project description:We have previously identified and characterized the phoenix auditory neuroprogenitors (ANPGs) as highly proliferative progenitor cells isolated from the A/J mouse cochlea. In the present study, we aimed at identifying signaling pathways responsible for the intrinsic high stemness of phoenix ANPGs. A transcriptomic comparison of traditionally low stemness ANPGs, isolated from C57Bl/6 and A/J mice at early passages, and high stemness phoenix ANPGs was performed.
