Project description:We reported the effect of condensin binding to the genome upon SET1 knockdown. ChIP-seq experiments of condensin (NCAPH2) were performed in control and SET1 knockdown cells. We found that condensin binding was significantly reduced upon SET1 knockdown.
Project description:Ribosome profiling to assess changes in ribosome occpancy upon overexpression of the RNA-binding protein Unkempt (most likely acts as a translational regulator) in human HeLa cell lines.
Project description:Human cancer cell lines were profiled by RNAseq following knockdown of RNA binding proteins, BRCA1, BRCA2, or treatment with siCTRL
Project description:1. evaluation of diagnostic importance of insulin like growth factor binding protein3 in patient with recently diagnosed as Colorectal cancer
2. correlation between the diagnostic efficacy of insulin like growth factor binding protein 3 with routine marker carcinoembryonic antigen.
Project description:This experiment analyzes the global proteome and phosphoproteome in YAP amplified cell lines upon YAP knockdown and/or MEK inhibition.