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Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults

ABSTRACT: Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults

PROVIDER: PRJEB53979 | ENA |

REPOSITORIES: ENA

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Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults

Project description:We molecularly characterized a class of histologically aggressive childhood liver cancers and showed that these tumors are clinically aggressive and that their observed histological features are associated with underlying recurrent molecular features. We proposed a diagnostic algorithm to identify these cancers using a combination of histological and molecular features, and our analysis suggested that these cancers may benefit from specialized treatment strategies that may differ from treatment guidelines for hepatoblastomas and hepatocellular carcinomas.

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Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults

Project description:Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults

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Project description:Hepatoblastomas with carcinoma features (HBCs) represent a biological spectrum of aggressive neoplasms in children and young adults

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Metabolic Alterations in JAK2 Mutant Hematopoietic Cells Represent Therapeutic Vulnerabilities for Myeloproliferative Neoplasms

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Proteomic Analysis of Canine Hepatobiliary Neuroendocrine Neoplasms

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