Genomics

Dataset Information

294

Cecal microbiota in FXR-/- and WT mice


ABSTRACT: Sequencing the cecal microbiota of FXR-/- and WT mice after vertical sleeve gastrectomy (VSG) and sham operations

PROVIDER: PRJEB6297 | ENA |

REPOSITORIES: ENA

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Publications


Bariatric surgical procedures, such as vertical sleeve gastrectomy (VSG), are at present the most effective therapy for the treatment of obesity, and are associated with considerable improvements in co-morbidities, including type-2 diabetes mellitus. The underlying molecular mechanisms contributing to these benefits remain largely undetermined, despite offering the potential to reveal new targets for therapeutic intervention. Substantial changes in circulating total bile acids are known to occur  ...[more]

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