Genomics

Dataset Information

0


ABSTRACT: Neural progenitors adopt specific identities by directly repressing all alternative progenitor transcriptional programmes

PROVIDER: PRJEB7682 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
ERR673319_1.fastq.gz Fastqsanger.gz
ERR673319_2.fastq.gz Fastqsanger.gz
ERR673320_1.fastq.gz Fastqsanger.gz
ERR673320_2.fastq.gz Fastqsanger.gz
ERR673321_1.fastq.gz Fastqsanger.gz
Items per page:
1 - 5 of 281
altmetric image

Publications

Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs.

Kutejova Eva E   Sasai Noriaki N   Shah Ankita A   Gouti Mina M   Briscoe James J  

Developmental cell 20160310 6


In the vertebrate neural tube, a morphogen-induced transcriptional network produces multiple molecularly distinct progenitor domains, each generating different neuronal subtypes. Using an in vitro differentiation system, we defined gene expression signatures of distinct progenitor populations and identified direct gene-regulatory inputs corresponding to locations of specific transcription factor binding. Combined with targeted perturbations of the network, this revealed a mechanism in which a pr  ...[more]

Similar Datasets

2015-01-01 | S-EPMC4383005 | BioStudies
2013-01-01 | S-EPMC3659286 | BioStudies
2015-01-01 | S-EPMC4631756 | BioStudies
2017-01-01 | S-EPMC5522468 | BioStudies
1000-01-01 | S-EPMC2657897 | BioStudies
2016-01-01 | S-EPMC4975379 | BioStudies
2016-01-01 | S-EPMC4728133 | BioStudies
2019-01-01 | S-EPMC6626847 | BioStudies
2011-01-01 | S-EPMC3183458 | BioStudies
2017-01-01 | S-EPMC5414248 | BioStudies