Project description:How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we find that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (KYA), and after no more than 8,000-year isolation period in Beringia. Native Americans diversified into two basal genetic branches around 13 KYA, one in North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians and Australo-Melanesians, the latter possibly through the ancestors of Aleutian Islanders. Putative relict populations in South America, including the historical Pericúes and Fuego-Patagonians, are not directly related to modern Australo-Melanesians.
Project description:Peruvian Native American individuals were genotyped as part of the Peruvian Genome Project (PGP). This data was used to infer population structure, demographic history and natural selection. We addressed question about gene flow across the Andes and Natural Selection in Andes and Amazon
Project description:The morphology of the first humans in the Americas (Paleoamericans) differs from that of Native Americans, and has raised the question of whether or not there are also differences in origin or genetics. A few populations who survived until relatively recently have been suggested to retain Paleoamerican morphology. One of these populations is from La Jolla. Here, we have generated genome sequence data from four La Jolla individuals in order to investigate these questions
This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
Project description:Using genome-wide information of Native Americans from Andes and Amazon we addressed questions about : the Andes-Amazon dichotomy, the Andean homogenization and how cultural and socioeconomic interactions revealed by archaeology were accompanied by gene flow, specifically in northern Peru. Moreover, this demographic history allowed for cases of positive natural selection in the high and arid Andes vs. the low Amazon tropical forest
