Dataset Information


Mus musculus

ABSTRACT: Expression data from mouse bone marrow macrophages from a strain intercross

ORGANISM(S): Mus musculus  



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Sex specific gene regulation and expression QTLs in mouse macrophages from a strain intercross.

Bhasin Jeffrey M JM   Chakrabarti Enakshi E   Peng Dao-Quan DQ   Kulkarni Aneesh A   Chen Xi X   Smith Jonathan D JD  

PloS one 20080116 1

<h4>Background</h4>A powerful way to identify genes for complex traits it to combine genetic and genomic methods. Many trait quantitative trait loci (QTLs) for complex traits are sex specific, but the reason for this is not well understood.<h4>Methodology/principal findings</h4>RNA was prepared from bone marrow derived macrophages of 93 female and 114 male F(2) mice derived from a strain intercross between apoE-deficient mice on the AKR and DBA/2 genetic backgrounds, and was subjected to transcr  ...[more]

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