Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Expression data from human liver cell line induced by PCB77

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA104103 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

PCB congener specific oxidative stress response by microarray analysis using human liver cell line.

De Supriyo S   Ghosh Somiranjan S   Chatterjee Raghunath R   Chen Y-Q YQ   Moses Linda L   Kesari Akanchha A   Hoffman Eric P EP   Dutta Sisir K SK  

Environment international 20100717 8


In this study we have examined the effect of exposure to different congeners of PCBs and their role in oxidative stress response. A metabolically competent human liver cell line (HepG2) was exposed with two prototype congeners of PCBs: coplanar PCB-77 and non-coplanar PCB-153. After the predetermined times of exposure (0-24h) at 70 μM concentration, the HepG2 cells showed significant apoptotic changes by fluorescent microscopy after 12h of exposure. Gene set enrichment analysis (GSEA) identified  ...[more]

Similar Datasets

| PRJNA104229 | ENA
| PRJNA133333 | ENA
| PRJNA133347 | ENA
2010-09-25 | GSE24338 | GEO
2010-09-25 | E-GEOD-24338 | ArrayExpress
| PRJNA341320 | ENA
2014-08-06 | E-GEOD-58734 | ArrayExpress
| GSE20463 | GEO
2011-02-19 | E-GEOD-20463 | ArrayExpress
| PRJNA96613 | ENA