Genomics

Dataset Information

0

Drosophila melanogaster


ABSTRACT: Chromatin IP of POF, HP1 and H3K9ac in S2 cells and salivary glands.

ORGANISM(S): Drosophila melanogaster  

PROVIDER: PRJNA105439 | ENA |

REPOSITORIES: ENA

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Publications

POF and HP1 bind expressed exons, suggesting a balancing mechanism for gene regulation.

Johansson Anna-Mia AM   Stenberg Per P   Pettersson Fredrik F   Larsson Jan J  

PLoS genetics 20071101 11


Two specific chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X chromosome is targeted by the male-specific lethal complex believed to mediate the 2-fold up-regulation of the X-linked genes, and the highly heterochromatic fourth chromosome is specifically targeted by the Painting of Fourth (POF) protein, which, together with heterochromatin protein 1 (HP1), modulates the expression level of genes on the fourth chromosome. Here we use chromatin imm  ...[more]

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