Genomics

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Comprehensive analysis of PPARα-dependent regulation of hepatic lipid metabolism by expression profiling - 5


ABSTRACT: Comprehensive analysis of PPARα-dependent regulation of hepatic lipid metabolism by expression profiling - 5

PROVIDER: PRJNA105443 | ENA |

REPOSITORIES: ENA

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Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling.

Rakhshandehroo Maryam M   Sanderson Linda M LM   Matilainen Merja M   Stienstra Rinke R   Carlberg Carsten C   de Groot Philip J PJ   Müller Michael M   Kersten Sander S  

PPAR research 20070101


PPARalpha is a ligand-activated transcription factor involved in the regulation of nutrient metabolism and inflammation. Although much is already known about the function of PPARalpha in hepatic lipid metabolism, many PPARalpha-dependent pathways and genes have yet to be discovered. In order to obtain an overview of PPARalpha-regulated genes relevant to lipid metabolism, and to probe for novel candidate PPARalpha target genes, livers from several animal studies in which PPARalpha was activated a  ...[more]

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