Dataset Information


Mus musculus

ABSTRACT: Comparison of the transcriptional profiles of the retinal pigmental epithelium/choroid from young and old mice

ORGANISM(S): Mus musculus  



altmetric image


The aged retinal pigment epithelium/choroid: a potential substratum for the pathogenesis of age-related macular degeneration.

Chen Huiyi H   Liu Bin B   Lukas Thomas J TJ   Neufeld Arthur H AH  

PloS one 20080604 6

<h4>Background</h4>Although the statement that age is the greatest risk factor for Age-related macular degeneration (AMD) is widely accepted, the cellular and molecular explanations for that clinical statement are not generally known. A major focus of AMD research is the retinal pigment epithelium (RPE)/choroid. The purpose of this study was to characterize the changes in the RPE/choroid with age that may provide a background for the development of AMD.<h4>Methodology/principal findings</h4>We c  ...[more]

Similar Datasets

2008-06-11 | E-GEOD-10965 | ArrayExpress
2008-03-29 | GSE10965 | GEO
2010-06-05 | E-GEOD-565 | ArrayExpress
2008-01-01 | S-EPMC2394659 | BioStudies
2018-01-01 | S-EPMC6162115 | BioStudies
2019-01-01 | S-EPMC6746706 | BioStudies
1000-01-01 | S-EPMC1182551 | BioStudies
2016-01-01 | S-EPMC4877072 | BioStudies
1000-01-01 | S-EPMC5894943 | BioStudies
2006-01-01 | S-EPMC2813776 | BioStudies