Dataset Information


Homo sapiens

ABSTRACT: Peripheral blood leukocyte genomic response one day post traumatic injury may predict early respiratory recovery

ORGANISM(S): Homo sapiens  



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Assessing statistical significance in microarray experiments using the distance between microarrays.

Hayden Douglas D   Lazar Peter P   Schoenfeld David D  

PloS one 20090616 6

We propose permutation tests based on the pairwise distances between microarrays to compare location, variability, or equivalence of gene expression between two populations. For these tests the entire microarray or some pre-specified subset of genes is the unit of analysis. The pairwise distances only have to be computed once so the procedure is not computationally intensive despite the high dimensionality of the data. An R software package, permtest, implementing the method is freely available  ...[more]

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