Genomics

Dataset Information

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Rattus norvegicus


ABSTRACT: MicroRNA expression profiling in diabetic GK rat model

ORGANISM(S): Rattus norvegicus  

PROVIDER: PRJNA110345 | ENA |

REPOSITORIES: ENA

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Publications

MicroRNA expression profiling in diabetic GK rat model.

Huang Bing B   Qin Wenming W   Zhao Botao B   Shi Yi Y   Yao Chengguo C   Li Jin J   Xiao Huasheng H   Jin Youxin Y  

Acta biochimica et biophysica Sinica 20090601 6


MicroRNAs (miRNAs), which are a newly identified class of small single-stranded non-coding RNAs, regulate their target genes via post-transcriptional pathway. It has been proved that miRNAs play important roles in many biological processes. To better understand miRNA function on type 2 diabetes, we used an oligonucleotide microarray to monitor miRNA expression profiles of Goto-Kakizaki (GK) and Wistar rats' skeletal muscle. It was found that seven miRNAs were downexpressed and two miRNAs were ov  ...[more]

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