Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Gene regulation by full length human adiponectin

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA110367 | ENA |

REPOSITORIES: ENA

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Publications

Transcriptome profiling in response to adiponectin in human cancer-derived cells.

Berger Emmanuelle E   Rome Sophie S   Vega Nathalie N   Ciancia Claire C   Vidal Hubert H  

Physiological Genomics 20100622 1


The adipocyte-derived hormone adiponectin exerts protective actions in several disorders, including some cancers. However, while growing data suggest that adiponectin could be an effective anticancer agent, its mechanism of action in cancer cells is still poorly known. Here, using microarrays, we identified a set of 1,301 genes commonly modulated in three cancer-derived cell lines in response to short-term stimulation with full-length recombinant human adiponectin. Most of these genes are involv  ...[more]

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